Structural and topographic dynamics of pulmonary histopathology and local cytokine profiles in Paracoccidioides brasiliensis conidia-infected mice.

• Main Authors: Damaris Lopera (Author), Tonny W Naranjo (Author), Oswaldo G Cruz (Author), Angela Restrepo (Author), Luz Elena Cano (Author), Henrique Leonel Lenzi (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2011-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND: Paracoccidioidomycosis (PCM), an endemic systemic mycosis caused by the fungus Paracoccidioides brasiliensis (Pb), usually results in severe lung damage in patients. METHODS AND FINDINGS: Considering the difficulties to sequentially study the infection in humans, this work was done in mi...