Edaravone Preserves Coronary Microvascular Endothelial Function After Ischemia/Reperfusion on the Beating Canine Heart In Vivo

We examined whether edaravone (3-methyl-1-phenyl-2-pyrazolin-5-one), a free radical scavenger, exerts its protective effect on coronary microvessels after ischemia/reperfusion (I/R) in vivo. Ninety-minute coronary occlusion followed by reperfusion was performed in 16 open-chest dogs with and without...

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Main Authors: Renan Sukmawan (Author), Toyotaka Yada (Author), Eiji Toyota (Author), Yoji Neishi (Author), Teruyoshi Kume (Author), Yoshiro Shinozaki (Author), Hidezo Mori (Author), Yasuo Ogasawara (Author), Fumihiko Kajiya (Author), Kiyoshi Yoshida (Author)
Format: Book
Published: Elsevier, 2007-01-01T00:00:00Z.
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