Formulation of Multicomponent Chrysin-Hydroxy Propyl β Cyclodextrin-Poloxamer Inclusion Complex Using Spray Dry Method: Physicochemical Characterization to Cell Viability Assessment

• Main Authors: Syed Sarim Imam (Author), Sultan Alshehri (Author), Wael A. Mahdi (Author), Ahmed M. Alotaibi (Author), Moath H. Alhwaifi (Author), Afzal Hussain (Author), Mohammad A. Altamimi (Author), Wajhul Qamar (Author)
• Format: Book
• Published: MDPI AG, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The work aimed to enhance chrysin (CHR) water solubility, dissolution, and in vitro antibacterial as well as cell viability. Chrysin binary, as well as ternary inclusion complex, were prepared using the spray drying method. The influence of an auxiliary component (poloxamer; PLX) was also assessed a...