Formulation of Multicomponent Chrysin-Hydroxy Propyl β Cyclodextrin-Poloxamer Inclusion Complex Using Spray Dry Method: Physicochemical Characterization to Cell Viability Assessment

• Главные авторы: Syed Sarim Imam (Автор), Sultan Alshehri (Автор), Wael A. Mahdi (Автор), Ahmed M. Alotaibi (Автор), Moath H. Alhwaifi (Автор), Afzal Hussain (Автор), Mohammad A. Altamimi (Автор), Wajhul Qamar (Автор)
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• Опубликовано: MDPI AG, 2022-12-01T00:00:00Z.
• Предметы: article
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The work aimed to enhance chrysin (CHR) water solubility, dissolution, and in vitro antibacterial as well as cell viability. Chrysin binary, as well as ternary inclusion complex, were prepared using the spray drying method. The influence of an auxiliary component (poloxamer; PLX) was also assessed a...