Polymer Coated Oncolytic Adenovirus to Selectively Target Hepatocellular Carcinoma Cells

• Main Authors: Mariangela Garofalo (Author), Federica Bellato (Author), Salvatore Magliocca (Author), Alessio Malfanti (Author), Lukasz Kuryk (Author), Beate Rinner (Author), Samuele Negro (Author), Stefano Salmaso (Author), Paolo Caliceti (Author), Francesca Mastrotto (Author)
• Format: Book
• Published: MDPI AG, 2021-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Despite significant advances in chemotherapy, the overall prognosis of hepatocellular carcinoma (HCC) remains extremely poor. HCC targeting strategies were combined with the tumor cell cytotoxicity of oncolytic viruses (OVs) to develop a more efficient and selective therapeutic system. OVs were coat...