The Compound <i>(E)</i>-2-Cyano-<i>N</i>,3-diphenylacrylamide (JMPR-01): A Potential Drug for Treatment of Inflammatory Diseases

• 主要な著者: Pablo Rayff da Silva (著者), Renan Fernandes do Espírito Santo (著者), Camila de Oliveira Melo (著者), Fábio Emanuel Pachú Cavalcante (著者), Thássia Borges Costa (著者), Yasmim Vilarim Barbosa (著者), Yvnni M. S. de Medeiros e Silva (著者), Natália Ferreira de Sousa (著者), Cristiane Flora Villarreal (著者), Ricardo Olímpio de Moura (著者), Vanda Lucia dos Santos (著者)
• フォーマット: 図書
• 出版事項: MDPI AG, 2022-01-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

The compound <i>(E)</i>-2-cyano-<i>N</i>,3-diphenylacrylamide (JMPR-01) was structurally developed using bioisosteric modifications of a hybrid prototype as formed from fragments of indomethacin and paracetamol. Initially, in vitro assays were performed to determine cell viab...