G-Quadruplex Linked DNA Guides Selective Transfection into Nucleolin-Overexpressing Cancer Cells

• Auteurs principaux: Mengxi Xiang (Auteur), Yongkui Li (Auteur), Jia Liu (Auteur), Jie Shi (Auteur), Yizhi Ge (Auteur), Chen Peng (Auteur), Yawen Bin (Auteur), Zheng Wang (Auteur), Lin Wang (Auteur)
• Format: Livre
• Publié: MDPI AG, 2022-10-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Gene therapy is a promising approach for treating tumors. Conventional approaches of DNA delivery depending on non-viral or viral vectors are unsatisfactory due to the concerns of biosafety and cell-targeting efficiency. The question how to deliver DNA into tumor cells efficiently and selectively is...