Qualitative Differences in Protection of PTP1B Activity by the Reductive Trx1 or TRP14 Enzyme Systems upon Oxidative Challenges with Polysulfides or H<sub>2</sub>O<sub>2</sub> Together with Bicarbonate
Protein tyrosine phosphatases (PTPs) can be regulated by several redox-dependent mechanisms and control growth factor-activated receptor tyrosine kinase phosphorylation cascades. Reversible oxidation of PTPs is counteracted by reductive enzymes, including thioredoxin (Trx) and Trx-related protein of...
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| Main Authors: | , , |
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| Format: | Book |
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MDPI AG,
2021-01-01T00:00:00Z.
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| Call Number: |
A1234.567 |
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| Copy 1 | Available |