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Qualitative Differences in Protection of PTP1B Activity by the Reductive Trx1 or TRP14 Enzyme Systems upon Oxidative Challenges with Polysulfides or H<sub>2</sub>O<sub>2</sub> Together with Bicarbonate

Protein tyrosine phosphatases (PTPs) can be regulated by several redox-dependent mechanisms and control growth factor-activated receptor tyrosine kinase phosphorylation cascades. Reversible oxidation of PTPs is counteracted by reductive enzymes, including thioredoxin (Trx) and Trx-related protein of...

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Bibliographic Details
Main Authors:	Markus Dagnell (Author), Qing Cheng (Author), Elias S.J. Arnér (Author)
Format:	Book
Published:	MDPI AG, 2021-01-01T00:00:00Z.
Subjects:	article
Online Access:	Connect to this object online.
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