Adenosine A1 Receptor Agonist (R-PIA) before Pilocarpine Modulates Pro- and Anti-Apoptotic Factors in an Animal Model of Epilepsy

• मुख्य लेखकों: Daniele Suzete Persike (लेखक), Rebeca Padrão Amorim Puccinelli (लेखक), Maria José da Silva Fernandes (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2021-04-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

We aimed to characterize the mechanisms involved in neuroprotection by R-PIA administered before pilocarpine-induced seizures. Caspase-1 and caspase-3 activities were assayed using fluorimetry, and cathepsin D, HSP-70, and AKT expression levels were assayed using Western Blot of hippocampal samples....