Computational studies reveal mechanism by which quinone derivatives can inhibit SARS-CoV-2. Study of embelin and two therapeutic compounds of interest, methyl prednisolone and dexamethasone

Background: Quinones are reactive to proteins containing cysteine residues and the main protease in Covid-19 contains an active site that includes Cys145. Embelin, a quinone natural product, is known to have antiviral activity against influenza and hepatitis B. Preliminary studies by our group also...

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Main Authors: Francesco Caruso (Author), Miriam Rossi (Author), Jens Z. Pedersen (Author), Sandra Incerpi (Author)
Format: Book
Published: Elsevier, 2020-12-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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