Clinical significance of matrix metalloproteinase 9 and tissue inhibitor of metalloproteinase 1 and 2 in Kawasaki disease

• Main Authors: Ki Wook Yun (Author), Sin Weon Sin (Author), Jung Ju Lee (Author), Soo Ahn Chae (Author), In Seok Lim (Author), Eung Sang Choi (Author), Byoung Hoon Yoo (Author), Mi-Kyung Lee (Author)
• Format: Book
• Published: Korean Pediatric Society, 2010-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Purpose : Kawasaki disease (KD) is a systemic vasculitis, a leading cause of pediatric acquired heart disease. Histopathological findings of coronary artery lesion (CAL) in KD indicate destruction of the coronary artery wall with diffuse vasculitis. Matrix metalloproteinases (MMPs) and their endogen...