Pharmacological evidence supporting a role for IL-1, IL-2 and serotonin in the inflammation induced by Schistosoma mansoni Soluble Egg Antigen (SEA) in rat paws

• Main Authors: C. M. F. Pacheco (Author), C. A. P. Tavares (Author), P. M. Z. Coelho (Author), O. A. Rocha (Author), J. M. M. Santos (Author), F. R. M. Prado (Author), J. N. Francischi (Author)
• Format: Book
• Published: Hindawi Limited, 1998-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

This study intended to characterize pharmacologically the mediator(s ) released in the inflammation induced by Soluble Egg Antigen (SEA), the main antigen released from eggs of Schistosoma mansoni, in rat hindpaws . A single intraplantar injection of 0.1-100 μg SEA at day zero induced a dose-depende...