CYP2D6 Genetic Variation and Its Implication for Vivax Malaria Treatment in Madagascar

• Main Authors: Rajeev K. Mehlotra (Author), Andrea Gaedigk (Author), Rosalind E. Howes (Author), Tovonahary A. Rakotomanga (Author), Arsene C. Ratsimbasoa (Author), Peter A. Zimmerman (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Plasmodium vivax is one of the five human malaria parasite species, which has a wide geographical distribution and can cause severe disease and fatal outcomes. It has the ability to relapse from dormant liver stages (hypnozoites), weeks to months after clearance of the acute blood-stage infection. A...