Spatial Lipidomics Reveals Anticancer Mechanisms of Bufalin in Combination with Cinobufagin in Tumor-Bearing Mice

• Main Authors: Jinghui Zhang (Author), Yanjun Hong (Author), Peisi Xie (Author), Yang Chen (Author), Lilong Jiang (Author), Zhiyi Yang (Author), Guodong Cao (Author), Zhongjian Chen (Author), Xuesong Liu (Author), Yong Chen (Author), Yongjiang Wu (Author), Zongwei Cai (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Bufalin (BFL) and cinobufagin (CBF) are the principal bioactive constituents of Chansu, a widely used traditional Chinese medicine (TCM). The synergistic effects of potential active components are responsible for the bioactivities of TCM. Our results showed that the cotreatment with BFL and CBF conf...