Second-Generation Antimitotics in Cancer Clinical Trials
Mitosis represents a promising target to block cancer cell proliferation. Classical antimitotics, mainly microtubule-targeting agents (MTAs), such as taxanes and vinca alkaloids, are amongst the most successful anticancer drugs. By disrupting microtubules, they activate the spindle assembly checkpoi...
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MDPI AG,
2021-07-01T00:00:00Z.
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