PknB remains an essential and a conserved target for drug development in susceptible and MDR strains of M. Tuberculosis

• Main Authors: Anamika Gupta (Author), Sudhir K. Pal (Author), Divya Pandey (Author), Najneen A. Fakir (Author), Sunita Rathod (Author), Dhiraj Sinha (Author), S. SivaKumar (Author), Pallavi Sinha (Author), Mycal Periera (Author), Shilpa Balgam (Author), Gomathi Sekar (Author), K. R. UmaDevi (Author), Shampa Anupurba (Author), Vijay Nema (Author)
• Format: Book
• Published: BMC, 2017-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background The Mycobacterium tuberculosis (M.tb) protein kinase B (PknB) which is now proved to be essential for the growth and survival of M.tb, is a transmembrane protein with a potential to be a good drug target. However it is not known if this target remains conserved in otherwise resis...