The Role of the Vagus Nerve: Modulation of the Inflammatory Reaction in Murine Polymicrobial Sepsis

• Main Authors: Wolfram Kessler (Author), Stephan Diedrich (Author), Pia Menges (Author), Tobias Ebker (Author), Michael Nielson (Author), Lars Ivo Partecke (Author), Tobias Traeger (Author), Katharina Cziupka (Author), Julia van der Linde (Author), Ralf Puls (Author), Alexandra Busemann (Author), Claus-Dieter Heidecke (Author), Stefan Maier (Author)
• Format: Book
• Published: Hindawi Limited, 2012-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The particular importance of the vagus nerve for the pathophysiology of peritonitis becomes more and more apparent. In this work we provide evidence for the vagal modulation of inflammation in the murine model of colon ascendens stent peritonitis (CASP). Vagotomy significantly increases mortality in...