Prognostic value of patient‐derived xenograft engraftment in pediatric sarcomas

• Main Authors: Helena Castillo‐Ecija (Author), Guillem Pascual‐Pasto (Author), Sara Perez‐Jaume (Author), Claudia Resa‐Pares (Author), Monica Vila‐Ubach (Author), Carles Monterrubio (Author), Ana Jimenez‐Cabaco (Author), Merce Baulenas‐Farres (Author), Oscar Muñoz‐Aznar (Author), Noelia Salvador (Author), Maria Cuadrado‐Vilanova (Author), Nagore G Olaciregui (Author), Leire Balaguer‐Lluna (Author), Victor Burgueño (Author), Francisco J Vicario (Author), Alejandro Manzanares (Author), Alicia Castañeda (Author), Vicente Santa‐Maria (Author), Ofelia Cruz (Author), Veronica Celis (Author), Andres Morales La Madrid (Author), Moira Garraus (Author), Maite Gorostegui (Author), Margarita Vancells (Author), Rosalia Carrasco (Author), Lucas Krauel (Author), Ferran Torner (Author), Mariona Suñol (Author), Cinzia Lavarino (Author), Jaume Mora (Author), Angel M Carcaboso (Author)
• Format: Book
• Published: Wiley, 2021-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract The goals of this work were to identify factors favoring patient‐derived xenograft (PDX) engraftment and study the association between PDX engraftment and prognosis in pediatric patients with Ewing sarcoma, osteosarcoma, and rhabdomyosarcoma. We used immunodeficient mice to establish 30 sub...