Challenges in preparing and implementing a clinical trial at field level in an Ebola emergency: A case study in Guinea, West Africa.

• Main Authors: Sara Carazo Perez (Author), Elin Folkesson (Author), Xavier Anglaret (Author), Abdoul-Habib Beavogui (Author), Emmanuel Berbain (Author), Alseny-Modet Camara (Author), Evelyn Depoortere (Author), Annabelle Lefevre (Author), Piet Maes (Author), Kristian Nødtvedt Malme (Author), Jean-Marie Denis Malvy (Author), Sien Ombelet (Author), Geertrui Poelaert (Author), Daouda Sissoko (Author), Alexis Tounkara (Author), Pierre Trbovic (Author), Pascal Piguet (Author), Annick Antierens (Author)
• Format: Bog
• Udgivet: Public Library of Science (PLoS), 2017-06-01T00:00:00Z.
• Fag: article
• Online adgang: Connect to this object online.

During the large Ebola outbreak that affected West Africa in 2014 and 2015, studies were launched to evaluate potential treatments for the disease. A clinical trial to evaluate the effectiveness of the antiviral drug favipiravir was conducted in Guinea. This paper describes the main challenges of th...