Characterizing drug-metabolizing enzymes and transporters that are bona fide CAR-target genes in mouse intestine

Intestine is responsible for the biotransformation of many orally-exposed chemicals. The constitutive androstane receptor (CAR/Nr1i3) is known to up-regulate many genes encoding drug-metabolizing enzymes and transporters (drug-processing genes/DPGs) in liver, but less is known regarding its effect i...

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Main Authors: Shinhee Park (Author), Sunny Lihua Cheng (Author), Julia Yue Cui (Author)
Format: Book
Published: Elsevier, 2016-09-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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