Rapidly Neutralizable and Highly Anticoagulant Thrombin-Binding DNA Aptamer Discovered by MACE SELEX
We present a rapidly neutralizable and highly anticoagulant thrombin-binding aptamer with a short toehold sequence, originally discovered by systematic evolution of ligands by exponential enrichment (SELEX) with microbead-assisted capillary electrophoresis (MACE). MACE is a novel CE-partitioning met...
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Main Authors: | Koji Wakui (Author), Toru Yoshitomi (Author), Akane Yamaguchi (Author), Maho Tsuchida (Author), Shingo Saito (Author), Masami Shibukawa (Author), Hitoshi Furusho (Author), Keitaro Yoshimoto (Author) |
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Format: | Book |
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Elsevier,
2019-06-01T00:00:00Z.
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