The SGLT-2 Inhibitor Dapagliflozin Has a Therapeutic Effect on Atherosclerosis in Diabetic ApoE−/− Mice

Background. Our study aimed to observe the effect of sodium glucose cotransporter-2 (SGLT2) inhibitor dapagliflozin on diabetic atherosclerosis and investigate the subsequent mechanism. Methods. Aortic atherosclerosis was induced in streptozotocin induced diabetic ApoE−/− mice by feeding with high-f...

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Main Authors: Weiling Leng (Author), Xinshou Ouyang (Author), Xiaotian Lei (Author), Mingxia Wu (Author), Liu Chen (Author), Qinan Wu (Author), Wuquan Deng (Author), Ziwen Liang (Author)
Format: Book
Published: Hindawi Limited, 2016-01-01T00:00:00Z.
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