Discovering a new class of antifungal agents that selectively inhibits microbial carbonic anhydrases

• Main Authors: Giannamaria Annunziato (Author), Laura Giovati (Author), Andrea Angeli (Author), Marialaura Pavone (Author), Sonia Del Prete (Author), Marco Pieroni (Author), Clemente Capasso (Author), Agostino Bruno (Author), Stefania Conti (Author), Walter Magliani (Author), Claudiu T. Supuran (Author), Gabriele Costantino (Author)
• Format: Book
• Published: Taylor & Francis Group, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Infections caused by pathogens resistant to the available antimicrobial treatments represent nowadays a threat to global public health. Recently, it has been demonstrated that carbonic anhydrases (CAs) are essential for the growth of many pathogens and their inhibition leads to growth defects. Princ...