Statin Modulation of Human T-Cell Proliferation, IL-1 and IL-17 Production, and IFN- T Cell Expression: Synergy with Conventional Immunosuppressive Agents

• Главные авторы: Ashmal Jameel (Автор), Kenneth G.-J. Ooi (Автор), Natasha R. Jeffs (Автор), Grazyna Galatowicz (Автор), Susan L. Lightman (Автор), Virginia L. Calder (Автор)
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• Опубликовано: Hindawi Limited, 2013-01-01T00:00:00Z.
• Предметы: article
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HMG-CoA reductase inhibitors (statins) have been demonstrated to be immunomodulatory for human immune-mediated disease and in experimental models. The aim of this study was to compare statin-mediated immunosuppressive effects on human T-cell responses in vitro with those of conventional immunosuppre...