The Chinese herbal formula QiangGuYin regulates the Wnt/β-catenin pathway in osteoblasts by intervening in the expression of miRNAs derived from osteoclast exosomes

• Main Authors: Binbin Tang (Author), Yifeng Yuan (Author), Shen Wang (Author), Shaohua Li (Author), Shifa Kang (Author), Caijian He (Author), Hang Zhou (Author), Mouhao Fang (Author), Tianpeng Chen (Author), Kang Liu (Author), Xiaolin Shi (Author)
• Format: Book
• Published: Elsevier, 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: To explore the effects of a TCM compound QiangGuYin (QGY) regulating osteoclast derived exosomal miRNAs on the Wnt/β-catenin pathway in osteoclast and osteoblasts. Methods: QGY containing serum was prepared to construct osteogenic and osteoclastic differentiation models. Setting up a non-...