Exploring the mechanism of aloe-emodin in the treatment of liver cancer through network pharmacology and cell experiments

• Main Authors: Mingyang Zhu (Author), Qingmin He (Author), Yanan Wang (Author), Liying Duan (Author), Kang Rong (Author), Yingying Wu (Author), Ye Ding (Author), Yang Mi (Author), Xiaoyang Ge (Author), Xiaocui Yang (Author), Yong Yu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Aloe-emodin (AE) is an anthraquinone compound extracted from the rhizome of the natural plant rhubarb. Initially, it was shown that AE exerts an anti-inflammatory effect. Further studies revealed its antitumor activity against various types of cancer. However, the mechanisms underlying th...