Inhibition of β-catenin signaling attenuates arteriovenous fistula thickening in mice by suppressing myofibroblasts

• Main Authors: Chung-Te Liu (Author), Shih-Chang Hsu (Author), Hui-Ling Hsieh (Author), Cheng-Hsien Chen (Author), Chun-You Chen (Author), Yuh-Mou Sue (Author), Tso-Hsiao Chen (Author), Yung-Ho Hsu (Author), Feng-Yen Lin (Author), Chun-Ming Shih (Author), Yan-Ting Shiu (Author), Po-Hsun Huang (Author)
• Format: Book
• Published: BMC, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Arteriovenous fistula (AVF) is the most important vascular access for hemodialysis; however, preventive treatment to maintain the patency of AVFs has not been developed. In endothelium, β-catenin functions in both the intercellular adherens complex and signaling pathways that ind...