Curcumin Inhibits NTHi-Induced MUC5AC Mucin Overproduction in Otitis Media via Upregulation of MAPK Phosphatase MKP-1

• المؤلفون الرئيسيون: Anuhya Sharma Konduru (مؤلف), Shingo Matsuyama (مؤلف), Byung-Cheol Lee (مؤلف), Kensei Komatsu (مؤلف), Jian-Dong Li (مؤلف)
• التنسيق: كتاب
• منشور في: Hindawi Limited, 2017-01-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Otitis media (OM), characterized by the presence of mucus overproduction and excess inflammation in the middle ear, is the most common childhood infection. Nontypeable Haemophilus influenzae (NTHi) pathogen is responsible for approximately one-third of episodes of bacteria-caused OM. Current treatme...