Nanoparticle-Mediated Dual Targeting: An Approach for Enhanced Baicalin Delivery to the Liver

• मुख्य लेखकों: Iman Saad Ahmed (लेखक), Hassan Medhat Rashed (लेखक), Hend Fayez (लेखक), Faten Farouk (लेखक), Rehab Nabil Shamma (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2020-01-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

In this study, water-soluble chitosan lactate (CL) was reacted with lactobionic acid (LA), a disaccharide with remarkable affinity to hepatic asialoglycoprotein (ASGP) receptors, to form dual liver-targeting LA-modified-CL polymer for site-specific drug delivery to the liver. The synthesized polymer...