Aronia melanocarpa polysaccharide ameliorates liver fibrosis through TGF-β1-mediated the activation of PI3K/AKT pathway and modulating gut microbiota

• Main Authors: Yingchun Zhao (Author), Xinglong Liu (Author), Chuanbo Ding (Author), Yinan Zheng (Author), Hongyan Zhu (Author), Zhiqiang Cheng (Author), Chunli Zhao (Author), Wencong Liu (Author)
• Format: Book
• Published: Elsevier, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The purpose of this experiment was to investigate the anti-hepatic fibrosis effect of Aronia melanocarpa polysaccharide (AMP) on TAA-induced liver fibrosis mice and its mechanism, as well as the changes in intestinal flora in vivo. This was established with a dose of 200 mg/kg TAA (i.p) once every t...