Tyrosine Nitroxidation Does Not Affect the Ability of α-Synuclein to Bind Anionic Micelles, but It Diminishes Its Ability to Bind and Assemble Synaptic-like Vesicles

• Asıl Yazarlar: Ana Belén Uceda (Yazar), Juan Frau (Yazar), Bartolomé Vilanova (Yazar), Miquel Adrover (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: MDPI AG, 2023-06-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Parkinson's disease (PD) is characterized by dopaminergic neuron degeneration and the accumulation of neuronal inclusions known as Lewy bodies, which are formed by aggregated and post-translationally modified α-synuclein (αS). Oxidative modifications such as the formation of 3-nitrotyrosine (3-...