Testosterone upregulates glial cell line-derived neurotrophic factor (GDNF) and promotes neuroinflammation to enhance glioma cell survival and proliferation

• Main Authors: Kouminin Kanwore (Author), Konimpo Kanwore (Author), Xiaoxiao Guo (Author), Ying Xia (Author), Han Zhou (Author), Lin Zhang (Author), Gabriel Komla Adzika (Author), Adu-Amankwaah Joseph (Author), Ayanlaja Abdulrahman Abiola (Author), Peipei Mu (Author), Piniel Alphayo Kambey (Author), Marie Louis N'dzie Noah (Author), DianShuai Gao (Author)
• Format: Book
• Published: BMC, 2023-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Testosterone contributes to male organism development, such as bone density, muscle development, and fat repartition. Estrogen (derived from testosterone) also contributes to female reproductive system development. Here, we investigated the effect of testosterone on glioma cells...