Identification and characterization of the Fasciola hepatica sodium- and chloride-dependent taurine transporter.

• Main Authors: Bulut Hamali (Author), Sandra Pichler (Author), Elisabeth Wischnitzki (Author), Klaus Schicker (Author), Melanie Burger (Author), Marion Holy (Author), Kathrin Jaentsch (Author), Martina Molin (Author), Eva Maria Sehr (Author), Oliver Kudlacek (Author), Michael Freissmuth (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2018-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The parasitic liver fluke Fasciola hepatica infests mainly ruminants, but it can also cause fasciolosis in people, who ingest the metacercariae encysted on plants. The drug of choice to treat fasciolosis is triclabendazole (TBZ), which has been on the market for several decades. This is also true fo...