Investigation of the Potential of Nebivolol Hydrochloride-Loaded Chitosomal Systems for Tissue Regeneration: In Vitro Characterization and In Vivo Assessment

• Principais autores: Noha Ibrahim Elsherif (Autor), Abdulaziz Mohsen Al-Mahallawi (Autor), Abdelfattah Ahmed Abdelkhalek (Autor), Rehab Nabil Shamma (Autor)
• Formato: Livro
• Publicado em: MDPI AG, 2021-05-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

In this study, we evaluated the synergistic effect of nebivolol hydrochloride (NVH), a third-generation beta-blocker and NO donor drug, and chitosan on the tissue regeneration. Ionic gelation method was selected for the preparation of NVH-loaded chitosomes using chitosan lactate and sodium tripolyph...