Investigation of the Potential of Nebivolol Hydrochloride-Loaded Chitosomal Systems for Tissue Regeneration: In Vitro Characterization and In Vivo Assessment

• Main Authors: Noha Ibrahim Elsherif (Author), Abdulaziz Mohsen Al-Mahallawi (Author), Abdelfattah Ahmed Abdelkhalek (Author), Rehab Nabil Shamma (Author)
• Format: Bog
• Udgivet: MDPI AG, 2021-05-01T00:00:00Z.
• Fag: article
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In this study, we evaluated the synergistic effect of nebivolol hydrochloride (NVH), a third-generation beta-blocker and NO donor drug, and chitosan on the tissue regeneration. Ionic gelation method was selected for the preparation of NVH-loaded chitosomes using chitosan lactate and sodium tripolyph...