Skin Barrier Damage and Itch: Review of Mechanisms, Topical Management and Future Directions

• Main Authors: Gil Yosipovitch (Author), Laurent Misery (Author), Ehrhardt Proksch (Author), Martin Metz (Author), Sonja Ständer (Author), Martin Schmelz (Author)
• Format: Book
• Published: Medical Journals Sweden, 2019-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Barrier damage, dry skin and itch are intricately linked and form the basis of many common skin diseases. Damage from environmental insults, or genetic or inflammatory causes, can impair the skin barrier, resulting in an increase in transepidermal water loss and activation of itch-associated nerve f...