Mixed Th1 and Th2 Mycobacterium tuberculosis-specific CD4 T cell responses in patients with active pulmonary tuberculosis from Tanzania.

• Main Authors: Patrizia Amelio (Author), Damien Portevin (Author), Klaus Reither (Author), Francis Mhimbira (Author), Maxmillian Mpina (Author), Anneth Tumbo (Author), Beatrice Nickel (Author), Hanspeter Marti (Author), Stefanie Knopp (Author), Song Ding (Author), Adam Penn-Nicholson (Author), Fatoumatta Darboe (Author), Khalid Ohmiti (Author), Thomas J Scriba (Author), Giuseppe Pantaleo (Author), Claudia Daubenberger (Author), Matthieu Perreau (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2017-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Mycobacterium tuberculosis (Mtb) and helminth infections elicit antagonistic immune effector functions and are co-endemic in several regions of the world. We therefore hypothesized that helminth infection may influence Mtb-specific T-cell immune responses. We evaluated the cytokine profile of Mtb-sp...