Effects of exogenous deoxyribonuclease I in collagen antibody-induced arthritis

• Main Authors: Kristína Macáková (Author), Veronika Borbélyová (Author), Mária Tekeľová (Author), Jakub Janko (Author), Michal Pastorek (Author), Richard Hokša (Author), Norbert Moravanský (Author), Emöke Šteňová (Author), Barbora Vlková (Author), Peter Celec (Author)
• Format: Book
• Published: BMC, 2024-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Rheumatoid arthritis (RA) is associated with a high concentration of extracellular DNA (ecDNA). This could be a consequence of the inflammation, but the ecDNA could also be involved in the unknown etiopathogenesis of RA. Clearance of ecDNA is hypothesized to prevent the developme...