OTUD3 suppresses the mTORC1 signaling by deubiquitinating KPTN

• Main Authors: Jiatao Li (Author), Dan Yang (Author), Yan Lin (Author), Wei Xu (Author), Shi-min Zhao (Author), Chenji Wang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Ubiquitination and deubiquitination modifications play pivotal roles in eukaryotic life processes, regulating protein dynamics via the ubiquitin-proteasome pathway. Dysregulation can impact disease development, including cancer and neurodegenerative disorders. Increasing evidence highlig...