Population Pharmacokinetic/Pharmacodynamic Model-Guided Dosing Optimization of a Novel Sedative HR7056 in Chinese Healthy Subjects

• Asıl Yazarlar: Ying Zhou (Yazar), Pei Hu (Yazar), Yuguang Huang (Yazar), Nuoer Sang (Yazar), Kaicheng Song (Yazar), Hongyun Wang (Yazar), Jinhua Wen (Yazar), Ji Jiang (Yazar), Xia Chen (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Frontiers Media S.A., 2018-11-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

HR7056 is a new benzodiazepine, showing more faster acting onset and recovery than currently available short-acting sedatives. To avoid inadequate anesthesia and predict return of cognition, allowing for immediate neurological evaluation, HR7056 pharmacokinetics and pharmacodynamics were characteriz...