Neurosphere Based Differentiation of Human iPSC Improves Astrocyte Differentiation

• Main Authors: Shuling Zhou (Author), Karolina Szczesna (Author), Anna Ochalek (Author), Julianna Kobolák (Author), Eszter Varga (Author), Csilla Nemes (Author), Abinaya Chandrasekaran (Author), Mikkel Rasmussen (Author), Susanna Cirera (Author), Poul Hyttel (Author), András Dinnyés (Author), Kristine K. Freude (Author), Hasan X. Avci (Author)
• Format: Book
• Published: Hindawi Limited, 2016-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Neural progenitor cells (NPCs) derived from human induced pluripotent stem cells (iPSCs) are traditionally maintained and proliferated utilizing two-dimensional (2D) adherent monolayer culture systems. However, NPCs cultured using this system hardly reflect the intrinsic spatial development of brain...