Development and validation of a hypoxia-stemness-based prognostic signature in pancreatic adenocarcinoma

• Main Authors: Xiong Tian (Author), Jing Zheng (Author), Wanlan Mou (Author), Guoguang Lu (Author), Shuaishuai Chen (Author), Juping Du (Author), Yufen Zheng (Author), Shiyong Chen (Author), Bo Shen (Author), Jun Li (Author), Na Wang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Pancreatic adenocarcinoma (PAAD) is one of the most aggressive and fatal gastrointestinal malignancies with high morbidity and mortality worldwide. Accumulating evidence has revealed the clinical significance of the interaction between the hypoxic microenvironment and cancer stemness in...