Cereblon Deficiency Contributes to the Development of Elastase-Induced Emphysema by Enhancing NF-κB Activation

• Main Authors: Eun-Young Heo (Author), Kyoung-Hee Lee (Author), Jisu Woo (Author), Jiyeon Kim (Author), Chang-Hoon Lee (Author), Kyung-Jin Lee (Author), Yun-Kyu Kim (Author), Chul-Gyu Yoo (Author)
• Format: Book
• Published: MDPI AG, 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cereblon (CRBN) has been shown to play an essential role in regulating inflammatory response and endoplasmic reticulum stress, thus mediating the development of various diseases. However, little is known about the roles of CRBN in chronic obstructive pulmonary disease (COPD) pathogenesis. We found t...