Methylxanthines induce structural and functional alterations of the cardiac system in zebrafish embryos

• Main Authors: Ram Manohar Basnet (Author), Daniela Zizioli (Author), Michela Guarienti (Author), Dario Finazzi (Author), Maurizio Memo (Author)
• פורמט: ספר
• יצא לאור: BMC, 2017-11-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

Abstract Background Zebrafish embryos are emerging as a model for pharmacological and toxicological studies. We used zebrafish embryos to study the general toxicity and cardiovascular effects of eight methylxanthines: aminophylline, caffeine, diprophylline, doxofylline, etophylline, 3-isobutyl-1-met...