LC-MS-based multivariate statistical analysis for the screening of potential thrombin/factor Xa inhibitors from Radix Salvia Miltiorrhiza

• Main Authors: Yi-Yao Yang (Author), Zhao-Yu Wu (Author), Hao Zhang (Author), Shi-Jun Yin (Author), Fang-Bo Xia (Author), Qian Zhang (Author), Jian-Bo Wan (Author), Jian-Li Gao (Author), Feng-Qing Yang (Author)
• Format: Book
• Published: BMC, 2020-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background The dry root and rhizome of Salvia miltiorrhiza Bunge, or Danshen, is a well-known traditional Chinese medicine with anticoagulant activity. Taking into account that thrombin (THR) and factor Xa (FXa) play crucial roles in the coagulation cascade, it is reasonable and meaningful...