In vitro study of radiosensitivity in colorectal cancer cell lines associated with Lynch syndrome

• Main Authors: Mingzhu Sun (Author), Jayne Moquet (Author), Stephen Barnard (Author), Hannah Mancey (Author), David Burling (Author), Rachel Baldwin-Cleland (Author), Kevin Monahan (Author), Andrew Latchford (Author), David Lloyd (Author), Simon Bouffler (Author), Christophe Badie (Author), Nicola A. Anyamene (Author), Elizabeth Ainsbury (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

IntroductionLynch syndrome patients have an inherited predisposition to cancer due to a deficiency in DNA mismatch repair (MMR) genes which could lead to a higher risk of developing cancer if exposed to ionizing radiation. This pilot study aims to reveal the association between MMR deficiency and ra...