Histological phenotypic subtypes predict recurrence risk and response to adjuvant chemotherapy in patients with stage III colorectal cancer

• Main Authors: Antonia K Roseweir (Author), James H Park (Author), Sanne ten Hoorn (Author), Arfon GMT Powell (Author), Susan Aherne (Author), Campbell SD Roxburgh (Author), Donald C McMillan (Author), Paul G Horgan (Author), Elizabeth Ryan (Author), Kieran Sheahan (Author), Louis Vermeulen (Author), James Paul (Author), Andrea Harkin (Author), Janet Graham (Author), Owen Sansom (Author), David N Church (Author), Ian Tomlinson (Author), Mark Saunders (Author), Tim J Iveson (Author), Joanne Edwards (Author)
• Format: Book
• Published: Wiley, 2020-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Histological 'phenotypic subtypes' that classify patients into four groups (immune, canonical, latent and stromal) have previously been demonstrated to stratify survival in a stage I-III colorectal cancer (CRC) pilot cohort. However, clinical utility has not yet been validated. Th...