Targeting delivery of simvastatin using ICAM-1 antibody-conjugated nanostructured lipid carriers for acute lung injury therapy

• Main Authors: Shu-Juan Li (Author), Xiao-Juan Wang (Author), Jing-Bo Hu (Author), Xu-Qi Kang (Author), Li Chen (Author), Xiao-Ling Xu (Author), Xiao-Ying Ying (Author), Sai-Ping Jiang (Author), Yong-Zhong Du (Author)
• Format: Book
• Published: Taylor & Francis Group, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Acute lung injury (ALI) is a critical illness without effective therapeutic modalities currently. Recent studies indicated potential efficacy of statins for ALI, while high-dose statins was suggested to be significant for attenuating inflammation in vivo. Therefore, a lung-targeted drug delivery sys...