Formononetin Ameliorates Renal Dysfunction, Oxidative Stress, Inflammation, and Apoptosis and Upregulates Nrf2/HO-1 Signaling in a Rat Model of Gentamicin-Induced Nephrotoxicity

• मुख्य लेखकों: Osama Y. Althunibat (लेखक), Mohammad H. Abukhalil (लेखक), Saleem H. Aladaileh (लेखक), Haitham Qaralleh (लेखक), Wesam Al-Amarat (लेखक), Manal A. Alfwuaires (लेखक), Abdulmohsen I. Algefare (लेखक), Nader Ibrahim Namazi (लेखक), Sahar J. Melebary (लेखक), Ahmad O. Babalghith (लेखक), Carlos Adam Conte-Junior (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Frontiers Media S.A., 2022-05-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Gentamicin (GEN) is a bactericidal aminoglycoside known to cause nephrotoxicity. Formononetin (FN) is a potent flavonoid that exhibits numerous promising pharmacological activities. In this study, we have assessed the nephroprotective efficacy of FN against GEN-induced renal injury in rats. Rats wer...