Mesenchymal Stromal Cell Exosomes Mediate M2-like Macrophage Polarization through CD73/Ecto-5'-Nucleotidase Activity

• Asıl Yazarlar: Kristeen Ye Wen Teo (Yazar), Shipin Zhang (Yazar), Jia Tong Loh (Yazar), Ruenn Chai Lai (Yazar), Hwee Weng Dennis Hey (Yazar), Kong-Peng Lam (Yazar), Sai Kiang Lim (Yazar), Wei Seong Toh (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: MDPI AG, 2023-05-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Mesenchymal stem/stromal cell (MSC) exosomes have been shown to alleviate immune dysfunction and inflammation in preclinical animal models. This therapeutic effect is attributed, in part, to their ability to promote the polarization of anti-inflammatory M2-like macrophages. One polarization mechanis...