Design of D-Amino Acids SARS-CoV-2 Main Protease Inhibitors Using the Cationic Peptide from Rattlesnake Venom as a Scaffold

• Asıl Yazarlar: Raphael J. Eberle (Yazar), Ian Gering (Yazar), Markus Tusche (Yazar), Philipp N. Ostermann (Yazar), Lisa Müller (Yazar), Ortwin Adams (Yazar), Heiner Schaal (Yazar), Danilo S. Olivier (Yazar), Marcos S. Amaral (Yazar), Raghuvir K. Arni (Yazar), Dieter Willbold (Yazar), Mônika A. Coronado (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: MDPI AG, 2022-04-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

The C30 endopeptidase (3C-like protease; 3CL^pro) is essential for the life cycle of SARS-CoV-2 (severe acute respiratory syndrome-coronavirus-2) since it plays a pivotal role in viral replication and transcription and, hence, is a promising drug target. Molecules isolated from...